Reaction scope study of pyrones 1 with amines 2^a.

Adduct	Pyrone	Amine	R	X	Yield, %	E-3 : Z-3 : keto-E-3
3a	1a	2a	Ph	H	87	82 : 13 : 5
3b	1b	2a	4-MeOC6H4	H	85	95 : 2 : 3
3c	1a	2b	Ph	OH	68	76 : 17 : 7
3d	1c	2b	4-ClC6H4	OH	81	76 : 17 : 7
3e	1b	2c	4-MeOC6H4	NH2	86	79 : 15 : 6
3f	1c	2c	4-ClC6H4	NH2	78	78 : 16 : 6
3g	1d	2c	2-Naph	NH2	90	79 : 13 : 8
3h	1e	2c	2-Th	NH2	90	89 : 8 : 3
3i	1f	2c	t-Bu	NH2	61	79 : 14 : 7

^aPyrone 1 (1.11 mmol) and amine 2 (1.11 mmol) were stirred in EtOH (6 mL) at 0 °C for 1 h.

^bThe reaction was performed at 20 °C for 2 h.

^cThe reaction was performed at 20 °C for 4 days, 2.22 mmol of the amine was used.