Synthesis of pyrido[1,2-a]quinoxaline-6,8-diones 7,8.
| Starting enaminone | Ar | R | Product 7, 8 | Yield 7, % | Yield 8, % | 7 : 8 (in DMSO-d6) |
|---|---|---|---|---|---|---|
| 3e | 4-MeOC6H4 | H | a | 72 | 89 | 81 : 19 |
| 3f | 4-ClC6H4 | H | b | 89 | 89 | 76 : 24 |
| 3h | 2-Th | H | c | 86 | 92 | 93 : 7 |
| 3j | 2-Th | Me | d | 85 | 80 | 97 : 3 |
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