Substrate scope: aryl bromidesa.
|
|---|
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a
Reaction conditions: dimethyl pent-4-yn-1-ylmalonate 1 (0.400 mmol), aryl bromide (0.500 mmol), K3PO4 (0.600 mmol), XPhos Pd G3 (8.0 μmol, 2 mol%), DMF (1 ml), 50 °C, 24 h.
b
Run for 4 h.
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