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Flow chart of the study. (A) Derivation of metaPRS for CAD in training dataset. (B) Validation of metaPRS in prospective cohorts. PRS, polygenic risk score; CAD, coronary artery disease; BP, blood pressure; BMI, body mass index; T2D, type 2 diabetes; TC, total cholesterol; LDL-C, LDL cholesterol; HDL-C, HDL cholesterol; TG, triglycerides.
