HANCD@urease catalyzed synthesis of THPPs.

Entry	R	R11	Time (min)	Yield (%)	Mp (°C)43–45, found (reported)
1	C6H5	OEt	80	96	240–242 (240–242)
2	4-Me2NC6H4	OEt	110	89	215–217 (217–218)
3	4-Me2NC6H4	OMe	90	90	215–217 (217–218)
4	4-O2NC6H4	OEt	60	98	<300 (<300)
5	4-ClC6H4	OEt	70	95	251–253 (252–254)
6	3-O2NC6H4	OEt	70	97	284–286 (286–288)
7	4-OH	OEt	110	90	216–219 (217–218)
8	4-OH	OMe	80	91	216–219 (217–218)
9	2-ClC6H4	OEt	90	92	219–221 (220–221)
10	2-O2NC6H4	OEt	70	89	185–187 (187–188)
11	2-O2NC6H4	OMe	55	90	185–187 (187–188)