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. 2022 May 7;238:114426. doi: 10.1016/j.ejmech.2022.114426

Fig. 4.

Fig. 4

(A) Dose-response curve for UA-30 in the antiviral assay against pSARS-CoV-2 and VSV-G infection in 293T-ACE2 cells. (B) Validation on the antiviral activity of UA-30 against authentic SARS-CoV-2 in Vero-E6 cells. (C) Antiviral activity of UA-30 against SARS-CoV-2 infection was detected by indirect immunofluorescence assay with chloroquine (CQ) as a positive control, scale bar = 200 mm. (D–E) Anti-SARS-CoV-2 efficacy of UA-30 on PsV variants in 293T-ACE2 cells, including E484K, D614G, N501Y (D) and Alpha, Beta, Gamma, Delta, Omicron (E).