Skip to main content
. 2022 May 7;238:114426. doi: 10.1016/j.ejmech.2022.114426

Table 1.

Antiviral activities of the title saponins UA-29 – UA-43 screened against pSARS-CoV-2-S at 10 and 40 μM, respectively.

No.
 Structure
 Inhibition rate (%)a
40 μM 10 μM
Image 1
UA-29 Image 2 toxicb toxicb
UA-30 Image 3 96.84 ± 5.40 46.81 ± 3.55
UA-31 Image 4 30.45 ± 2.13 −2.49 ± 0.24
UA-32 Image 5 27.44 ± 4.11 16.94 ± 2.35
UA-33 Image 6 19.25 ± 1.03 10.32 ± 2.10
UA-34 Image 7 14.51 ± 1.06 −7.27 ± 1.03
UA-35 Image 8 33.08 ± 1.02 27.35 ± 2.51
UA-36 Image 9 −21.66 ± 1.20 −31.75 ± 4.32
UA-37 Image 10 51.87 ± 2.23 41.08 ± 1.89
UA-38 Image 11 toxicb toxicb
UA-39 Image 12 92.49 ± 3.78 59.23 ± 4.21
UA-40 Image 13 58.74 ± 5.13 32.52 ± 2.59
UA-41 Image 14 1.58 ± 0.34 0.47 ± 0.08
UA-42 Image 15 85.69 ± 1.33 36.26 ± 2.45
UA-43 Image 16 49.47 ± 3.08 28.16 ± 2.22
Sal-C / 98.30 ± 2.62 80.25 ± 2.56
a

Data are expressed as the mean ± SD of three experiments.

b

Title saponins showed significant cytotoxicity at corresponding concentrations, and the inhibition rate could not be calculated.