Table 2.

Overview of microglia-enriched markers

Marker (gene)	Name	Cell type	Function	Reference
TMEM119	Transmembrane Protein 119	Microglia	Uncertain	Bennett et al. (2016), Satoh et al. (2016)
P2RY12	Purinergic Receptor P2Y12	Microglia	Purinergic receptor required for microglia chemotaxis in response to CNS injury	Bennett et al. (2016), Butovsky et al. (2014)
CSF1R	Colony Stimulating Factor 1 Receptor	Microglia and other myeloid lineage cells	Cell surface receptor that directly controls the development, survival, and maintenance of microglia and plays a pivotal role in neuroinflammation	Chitu et al. (2016), Erblich et al. (2011), Nandi et al. (2012)
CX3CR1	C-X3-C motif chemokine receptor 1	Microglia and other myeloid lineage cells	Chemokine receptor critical in controlling microglia numbers, synaptic pruning, and functional brain connectivity	Jones et al. (2010)
TREM2	Triggering Receptor Expressed on Myeloid Cells 2	Microglia and other myeloid lineage cells	Regulatory protein involved in microglia activation and phagocytosis of apoptotic neurons	Colonna (2003), Neumann and Takahashi (2007)
AIF1	Ionized Calcium-Binding Adapter Molecule 1	Microglia and other myeloid lineage cells	Cytoplasmic protein involved in microglia motility, membrane reorganization and phagocytosis	Imai et al. (1996), Sasaki et al. (2001)