Table 2.

Gene expression of 5-HT related genes in the ileum of naïve ICR mice

Gene	Vehicle	PS128
Tph1	1.0 ± 0.40	3.2 ± 1.18***
Tph2	1.0 ± 0.67	0.8 ± 0.87
Chga	1.0 ± 0.53	0.7 ± 0.31*
Slc6a4	1.0 ± 0.46	0.5 ± 0.15***
Htr3a	1.0 ± 0.61	1.0 ± 0.70
Htr4	1.0 ± 0.93	0.2 ± 0.17***
Maoa	1.0 ± 0.44	1.2 ± 0.29

Gene expression levels of Tph1, Tph2, Chga, Slc6a4, Htr3a, Htr4, and Maoa were quantified by real-time PCR relative to the expression of Gapdh. Values were expressed as mean ± SEM and analyzed using an unpaired t test

^*P < 0.05; **P < 0.01; ***P < 0.001 versus the vehicle control group