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. 2022 May 7;20(4):2385–2485. doi: 10.1007/s10311-022-01424-x

Table 10.

Influence of antibiotics on methane outcome during the anaerobic digestion process

Feedstock Antibiotic Dosage Methane production References
Dewatered sludge Roxithromycin 0–1 mg L−1 Reduced from 0.164 L per gVS to 0.151 L per gVS Ni et al. (2020a)
Swine manure Chlortetracycline 0–0.5 g per kg TS Reduced by up to 37.3% Yin et al. (2016)
Swine manure Oxytetracycline Inhibited gas yield by 8.3–22.1% Yin et al. (2016)
Dewatered sludge Sulphadimethoxine 100 mg L−1 Increased methane output by 39–52% Zhi et al. (2019)
Dewatered sludge Oxytetracycline Enhanced methane output by 1–25% Zhi et al. (2019)
Cattle manure Ceftiofur 0.2–250 mg L−1 Reduced methane output by 20% at dosage > 50 mg L−1 Flores-Orozco et al. (2020)
Cattle manure Chlortetracycline 0.04–1.28 mg L−1 Reduced methane output by 12–33% at concentration > 0.64 mg L−1 Andriamanohiarisoamanana et al. (2020)
Cattle manure Oxytetracycline Reduced methane yield by 20–32% Andriamanohiarisoamanana et al. (2020)

The table demonstrates that the existence of most antibiotics can reduce the anaerobic digestion performance due to their inhibitory effect on microorganisms