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Bidirectional Permeability of Test Compounds
| Compound ID | Bi-Directional CACO2 Permeability | |
|---|---|---|
| Papp (Apical to Basal) x 10−6 cm/s | Papp (Basal to Apical) x 10−6 cm/s | |
| 7a | 9.3 ± 3.1 | 7.9 ± 2.3 |
| 7b | 6.4 ± 1.5 | 4.2 ± 0.9 |
| 7e | 17.3 ± 2.9 | 9.9 ± 3.1 |
| 7m | 2.4 ± 1.7 | 3.9 ± 1.9 |
| Propranolol | 29.0 ± 1.2 | 21.1 ± 0.3 |
| Atenolol | 1.4 ± 0.2 | 3.0 ± 0.2 |
Note: Data represented as mean ± SD; N = 3.
