Table 2.
Comparison of Tumor characteristics and Laboratory Studies for Ruptured Versus Nonruptured Hepatocellular Carcinoma.
| Characteristic | Ruptured (n = 57) | Non-ruptured (n = 1394) | P value |
|---|---|---|---|
| Mean tumor sizein cm(SD) | 7.99 (3.93) | 5.73 (4.34) | <0.001 |
| Tumor ≥ 5 cm | 39 (88.4%) | 585 (42.0%) | <0.001 |
| Tumor ≥10 cm | 12 (21.1%) | 230 (16.5%) | 0.37 |
| Multiple tumors | 11 (19.3%) | 461 (33.1%) | 0.03 |
| Cirrhosis | 22/53 (41.5%) | 995/1375 (72.4%) | <0.001 |
| Mean bilirubinin mg/dL (SD) | 1.18 (1.16) | 1.59 (2.43) | 0.21 |
| Mean albuminin mg/dL (SD) | 3.29 (0.69) | 3.56 (0.70) | 0.004 |
| Mean INR | 1.19 (0.21) | 1.16 (0.27) | 0.45 |
| Mean platelet countx103/uL(SD) | 187.6 (93) | 166.9 (96.1) | 0.11 |
| Mean creatininein mg/dl(SD) | 1.24 (0.95) | 1.03 (0.80) | 0.69 |
| Mean ASTin IU/L (SD) | 94.4 (101.8) | 82.8 (77.4) | 0.39 |
| Mean ALTin IU/L (SD) | 66.2 (57.2) | 65 (57.5) | 0.87 |
| Mean AFP (SD) | 13,120 (50,890) | 11,754 (58,182) | 0.73 |
| Normal AFP<20 ng/dL | 21/56 (37.5%) | 559/1387 (40.3%) | 0.68 |
| AFP ≥ 1000 ng/dL | 15 (26.3%) | 289 (20.7%) | 0.32 |
| Mean neutrophil/lymphocyte ratio(SD) | 8.27 (8.71) | 3.26 (3.16) | <0.001 |