Table 3.
Operational Characteristics of Various Strategies to Detect Luminal Stenosis ≥70%.
| Variable | Sensitivity | Specificity | PPV | NPV | P |
|---|---|---|---|---|---|
| Troponin I | 22% | 94% | 50% | 82% | 0.14 |
| ≥2 CV Risk Factors | 92% | 14% | 26% | 83% | 0.63 |
| ≥3 CV Risk Factors | 33% | 57% | 20% | 72% | 0.54 |
| ASCVD High Risk | 83% | 32% | 30% | 85% | 0.29 |
| DSE/SPECT | 50% | 80% | 43% | 84% | 0.14 |
| MESA High Risk | 100% | 10% | 28% | 100% | 0.29 |
| CAC >346 | 100% | 31% | 31% | 100% | 0.04 |
ASCVD, atherosclerosis cardiovascular disease risk; CAC, coronary calcium score; CV, cardiovascular; DSE, dobutamine stress echocardiogram; MESA, Multi-Ethnic Study of Atherosclerosis; NPV, negative predictive value; SPECT, single-photon emission computed tomography; PPV, positive predictive value.