Table 1.

Diagnosis of Pathological Fatigue.

Necessary [all must be present]

Significant fatigue

Diminished energy

Increased need to rest disproportionate to level of activity

Anciliary [at least five of these symptoms must be present]

Experience of limb heaviness of generalized weakness

Diminished concentration or attention

Decreased motivation or interest to engage in usual activities

Insomnia or hypersomnia

Experience sleep as unrefreshing or nonrestorative

Perceived need to struggle to overcome inactivity

Marked emotional reactivity to feeling fatigued

Perceived problems with short term memory

Postexertional malaise for several hours

Modified from Cancer-related fatigue: ESMO Clinical Practice Guidelines for diagnosis and treatment by A. Fabi. Annals of Oncology, Volume 31, Issue 6, 2020.