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. 2022 Jan 22;30(4):1754–1774. doi: 10.1016/j.ymthe.2022.01.033

Figure 1.

Figure 1

SOCE proteins are increased in PACs and experimental AP

(A and B) Expression of proteins (A) and mRNAs (B) of SOCE channels and regulators in CER-AP pancreata (seven cerulein injections) 12 h after disease induction. (C and D) Expression of proteins (C) and mRNAs (D) of SOCE channels and regulators in TLCS-AP pancreata (5 mM TLCS) 6 h after disease induction. (E and F) Expression of proteins (E) and mRNAs (F) of SOCE channels and regulators in isolated mouse PACs stimulated with CCK (100 nM) for 1 h. (G and H) Expression of proteins (G) and mRNAs (H) of SOCE channels and regulators in isolated mouse PACs stimulated with TLCS (500 μM) for 30 min. Data are from 6–13 mice per group, shown as mean ± SEM.