Fig. 5. Down-regulation of FOXF1 partly abrogated PVT1-knockdown-mediated anti-proliferation and pro-apoptosis effect in breast cancer cells. MCF-7 cells were transfected with si-con, si-PVT1#1, or si-PVT1#1 + si-FOXF1, followed by the measurement of cell viability (A), colony formation ability (B), cell cycle distribution (C), and apoptotic rate (D). *P < 0.05.
