Fig. 6. Knockdown of PVT1 suppressed tumor growth by promoting FOXF1 expression in vivo. MCF-7 cells stably transfected with sh-con or sh-PVT1 were inoculated into nude mice (n = 6). (A) Tumor volume was measured using a caliper every three days for 21 days after injection. (B) Tumors of xenograft mice in sh-con and sh-PVT1 group were photographed and weighted at day 21 after injection. (C and D) The expression patterns of PVT1 and FOXF1 protein in excised tumor tissues. *P < 0.05.
