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. 2022 May 6;5(5):e2210743. doi: 10.1001/jamanetworkopen.2022.10743

Table 2. Baseline Characteristics of All COVID-19–Positive Psychiatric Inpatients and COVID-19–Related Deaths.

Characteristic All patients with COVID-19, No. (%) (N = 969) COVID-19–related deathsa
No. (%) (n = 38 [3.9%]) Crude OR (95% CI)
Clinical characteristics
Age, mean (SD), y 52.8 (14.2) 67.0 (10.6) 1.12 (1.08-1.16)b
Age group, y
18-44 269 (27.8) 1 (2.6) 1 [Reference]
45-54 186 (19.2) 2 (5.3) 2.91 (0.26-32.36)
55-64 295 (30.4) 9 (23.7) 8.43 (1.06-67.00)b
≥65 219 (22.6) 26 (68.4) 36.10 (4.86-268.28)b
Sex
Male 723 (74.6) 29 (76.3) 1 [Reference]
Female 246 (25.4) 9 (23.7) 0.91 (0.42-1.95)
Race and ethnicity
Asian or Pacific Islander 54 (5.6) 5 (13.2) 2.44 (0.83-7.15)
Black 410 (42.3) 13 (34.2) 0.78 (0.36-1.71)
Latinx 156 (16.1) 5 (13.2) 0.79 (0.28-2.26)
White 324 (33.4) 13 (34.2) 1 [Reference]
Other or unknownc 25 (2.6) 2 (5.3) 2.08 (0.44-9.78)
Smoking status
Nonsmoker 492 (50.8) 15 (39.5) 1 [Reference]
Smoker 172 (17.8) 6 (15.8) 1.15 (0.44-3.01)
Status not available 305 (31.5) 17 (44.7) 1.88 (0.92-3.82)b
BMI group
Normal (≤25) 283 (29.2) 11 (28.9) 1 [Reference]
Overweight (26-30) 372 (38.4) 16 (42.1) 1.11 (0.51-2.43)
Low-risk obesity (31-35) 206 (21.3) 6 (15.8) 0.74 (0.27-2.04)
Moderate- to high-risk obesity (>35) 108 (11.1) 5 (13.2) 1.20 (0.41-3.54)
Chronic respiratory disease
Yes 80 (8.3) 4 (10.5) 1.32 (0.46-3.83)
No 889 (91.7) 34 (89.5) 1 [Reference]
Diabetes
Yes 136 (14.0) 12 (31.6) 3.00 (1.48-6.11)b
No 833 (86.0) 26 (68.4) 1 [Reference]
Heart disease
Yes 47 (4.9) 8 (21.1) 6.09 (2.63-14.17)b
No 922 (95.1) 30 (78.9) 1 [Reference]
Hypertension
Yes 214 (22.1) 17 (44.7) 3.02 (1.56-5.83)b
No 755 (77.9) 21 (55.3) 1 [Reference]
Affective psychotic disorder
Yesd 452 (46.6) 16 (42.1) 0.83 (0.43-1.59)
Noe 517 (53.4) 22 (57.9) 1 [Reference]
Facility size, mean (SD) No. of patients 199.8 (60.9) 213.8 (54.2) 1.00 (1.00-1.01)
Hospital region
New York City and Long Island 653 (67.4) 23 (60.5) 1 [Reference]
Hudson River 307 (31.7) 15 (39.5) 1.41 (0.72-2.74)
Central or Western New York 9 (0.9) 0 NA
Psychotropic medication class
First-generation antipsychotic
Yes 611 (63.0) 23 (60.5) 0.89 (0.46-1.74)
No 358 (37.0) 15 (39.5) 1 [Reference]
Second-generation antipsychotic
Yes 870 (89.8) 33 (86.8) 0.74 (0.28-1.94)
No 99 (10.2) 5 (13.2) 1 [Reference]
Mood stabilizers
Yes 541 (55.8) 19 (50.0) 0.78 (0.41-1.50)
No 428 (44.2) 19 (50.0) 1 [Reference]
Benzodiazepines
Yes 502 (51.8) 16 (42.1) 0.67 (0.35,1.28)
No 467 (48.2) 22 (57.9) 1 [Reference]
Antidepressants
Yes 261 (26.9) 6 (15.8) 0.50 (0.21-1.20)b
No 708 (73.1) 32 (84.2) 1 [Reference]

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); NA, not applicable; OR, odds ratio.

a

Estimates show the crude associations between clinical characteristics, psychotropic medication class, and COVID-19 death among inpatients with COVID-19.

b

P < .10.

c

Includes Native American, multiple races, or “other race.”

d

Includes schizoaffective disorder, bipolar I disorder, and major depressive disorder with psychotic features.

e

Includes schizophrenia, delusional disorder, and schizotypal disorder.