Table 4. Case Fatality and Adjusted Odds Ratios of COVID-19 Mortality by Psychotropic Medication Exposures.

Psychotropic medication	Patients with COVID, No. (n = 969)	COVID-19–related deaths, No. (%) (n = 38 [3.9%])	Odds ratio (95% CI)
Psychotropic medication	Patients with COVID, No. (n = 969)	COVID-19–related deaths, No. (%) (n = 38 [3.9%])	Medications only	Adjusted for age and sex	Fully adjusted^a
First-generation antipsychotic
Chlorpromazine^b	47	0	NA	NA	NA
Second-generation antipsychotic
Olanzapine	398	14 (3.5)	0.54 (0.26-1.09)	0.61 (0.30-1.27)	0.61 (0.29-1.29)
Clozapine	341	6 (1.8)	0.25 (0.10-0.62)^c	0.40 (0.16-1.03)	0.43 (0.17-1.12)
Risperidone	157	3 (1.9)	0.32 (0.10-1.07)	0.35 (0.10-1.20)	0.42 (0.12-1.45)
Paliperidone	67	2 (3.0)	0.62 (0.14-2.71)	0.51 (0.11-2.32)	0.54 (0.12-2.49)
Mood stabilizers
Valproic acid	363	16 (4.4)	1.33 (0.68-2.59)	1.58 (0.78-3.16)	1.48 (0.72-3.03)
Antidepressants
Sertraline	62	1 (1.6)	0.36 (0.05-2.67)	0.46 (0.06-3.52)	0.53 (0.07-4.08)
Citalopram	70	1 (1.4)	0.36 (0.05-2.67)	0.38 (0.05-2.94)	0.46 (0.06-3.57)
Escitalopram^b	47	0	NA	NA	NA

Abbreviation: NA, not applicable.

^{^a}

The fully adjusted odds ratios controlled for age, sex, diabetes, hypertension, heart disease, and other medications in the model.

^{^b}

Could not be retained for statistical modeling owing to 0 deaths.

^{^c}

P < .01, where α′ = .05/4 = .0125 to correct for multiple comparisons.