Fig. 1.

Polygonum tinctorium suppresses dextran sulfate sodium (DSS)-induced colitis.

(A) A graphical representation of the average percent weight loss in the colitis and P. tinctorium groups, relative to the weights at the start of DSS treatment. ∗P < 0.05; ∗∗P < 0.01. (B) Colons harvested from the mice in the colitis and P. tinctorium groups on Day 12. (C) A graphical representation of the colon lengths harvested from the mice in the colitis and P. tinctorium groups on Day 12. (D) Histological samples of hematoxylin and eosin-stained colons observed at 40 × , 100 × , and 200 × magnifications. (E) The extent of inflammatory cell infiltration and crypt and mucosal epithelial losses. Data are expressed as the means ± standard error of the mean of groups of 8 mice.