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. 2018 Jan 12;8(5):2723–2732. doi: 10.1039/c7ra12948c

Estimated regression coefficients for the quadratic polynomial model and the analysis of variance (ANOVA) for the experimental resultsa.

Parameter Coefficient estimate Standard error Sum of squares DF Mean square F value
Model 37.53 9 4.17 251.40***
Intercept 16.85 0.058 1
X 1 0.26 0.046 0.55 1 0.55 32.92***
X 2 0.78 0.046 4.82 1 4.82 290.63***
X 3 1.65 0.046 21.65 1 21.65 1305.18***
X 1 X 2 2.500 × 10−3 0.064 2.500 × 10−5 1 2.500 × 10−5 1.507 × 10−3NS
X 1 X 3 −0.13 0.064 0.068 1 0.068 4.08NS
X 2 X 3 −0.21 0.064 0.18 1 0.18 10.64*
X 1 2 −0.43 0.063 0.78 1 0.78 46.88***
X 2 2 −0.90 0.063 3.45 1 3.45 207.80***
X 3 2 −1.10 0.063 5.12 1 5.12 308.42***
Residual 0.12 7 0.017
Lack of fit 0.091 3 0.030 4.89NS
Pure error 0.025 4 6.320 × 10−3
R 2 0.9969 Adj R2 0.9930
CV% 0.82 Pred R2 0.9603
Press 1.49 Adeq. precision 49.430
a

*P < 0.05, **P < 0.01, ***P < 0.001, NS – not significant.