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. Author manuscript; available in PMC: 2022 May 7.
Published in final edited form as: Curr Top Dev Biol. 2015 Jan 22;111:97–134. doi: 10.1016/bs.ctdb.2014.11.004

Figure 4.

Figure 4

Loss of primary cilia affects cardiac NCCs. Ttc21baln mutant has cardiac NCC defects. (A) Whole-mount image of an e14.5 Ttc21baln mutant with systemic edema suggestive of cardiopulmonary dysfunction. (B) Xgal staining in an e11.5 Wnt1-Cre;R26R embryo to trace the NCC lineage. (C) Xgal staining in an e11.5 Ttc21balnWnt1-Cre;R26R embryo. Dotted white lines outline the heart. Solid white lines indicate the degree of cardiac NCC migration into the septating outflow tract.