Table 1.
Characteristics of clinical practice guidelines that assessed COVID-19 management in children (2021).
| Author | Country | Topics addressed | Date of publication or update | Methodology used to reach recommendations | Methodology used for grading the strength of recommendations | Claimed to have performed systematic reviews of the evidence | Showed the benefits and harms of the interventions | Used structured frameworks for decision-making |
|---|---|---|---|---|---|---|---|---|
| ACR | USA and Canada | MIS-C (diagnosis and management) | Apr-2021 | Expert consensus was built through a modified Delphi process (anonymous voting and webinar discussion) | ACR (Expert consensus) | Yes | Yes, only narratively | No |
| AEP | Spain | Epidemiology, diagnosis, treatment, and prevention of COVID-19 | Mar-2021 | GRADE | GRADE | Yes | Yes, either using SoF tables or narratively, depending on the question | No |
| NIH | USA | Management of COVID-19 | Apr-2021 | NIH methodology (blind vote) | NIH criteria | Yes | Yes, only narratively | No |
| SSICM and PIGS | Switzerland | MIS-C (diagnosis and management) | May-2021 | Expert consensus was built through a modified Delphi process | It appears to be an expert consensus | No (performed a “focused literature review”) | No | No |
| NHMRC | Australia | Prevention, diagnosis, and management of COVID-19 | Oct-2021 | GRADE | GRADE | Yes | Yes, either using SoF tables or narratively, depending on the question | No |
ACR: American College of Rheumatology.
AEP: Spanish Pediatric Association.
NIH: National Institutes of Health.
SSICM and PIGS: Swiss Society of Intensive Care Medicine and the Pediatric Infectious Diseases Group of Switzerland.
NHMRC: Australian National Health and Medical Research Council.