Fig. 5.

Organ failure and mortality curves over 28 days among 24-h phenotypes. Number of organ failures and mortality according to PedSep-A, B, C, and D phenotype over 28 days. Both short-term mortality (panel A) and organ failure (panel B) show significant differences by phenotype (p < 0.001). The mean numbers of organ failures and 95% confidence intervals (CI) are calculated each day by non-nested observation, where we do not carry forward the OFI at the time the patient leaves the PICU alive or dead. As a reference for patients at risk for Panel B, Panel C shows the number of children remaining in the PCU at day 0, 7, 14, 21, and 28