Table 3.
Antibiotic Susceptibility of clinical P. aeruginosa isolates before and after incubation with Sodium hypochlorite
| Antibiotic (Classes) | Before n (%) | After n (%) | P-value | ||||
|---|---|---|---|---|---|---|---|
| Sensitive | Intermediate | Resistance | Sensitive | Intermediate | Resistance | ||
| Meropenem(Carbapenems) | 78(65) | 8(6.7) | 34(28.3) | 65(54.2) | 15(12.5) | 40(33.3) | < 0.001 |
| Imipenem (Carbapenems) | 25(20.8) | 40(33.3) | 55(45.8) | 16(13.3) | 40(33.3) | 64(53.3) | 0.004 |
| Tobramycin(Aminoglycosides) | 93(77.5) | 3(2.5) | 24(20) | 83(69.2) | 9(7.5) | 28(23.3) | 0.002 |
| Amikacin (Aminoglycosides) | 89(74.2) | 11(9.2) | 20(16.7) | 82(68.3) | 12(10) | 26(21.7) | 0.016 |
| Gentamicin (Aminoglycosides) | 91(75.8) | 6(5) | 23(19.2) | 81(67.5) | 11(9.2) | 28(23.3) | 0.002 |
| Cefepime (Cephalosporins) | 85(70.8) | 14(11.7) | 21(17.5) | 76(63.3) | 18(15) | 26(21.7) | 0.004 |
| Cefoxitin(Cephalosporins) | 0(0) | 0(0) | 120(100) | 0(0) | 0(0) | 120(100) | - |
| Ceftazidime (Cephalosporins) | 66(55) | 26(21.7) | 28(23.3) | 60(50) | 28(23.3) | 32(26.7) | 0.031 |
| Levofloxacin (Fluoroquinolones) | 50(41.7) | 30(25) | 40(33.3) | 44(36.7) | 33(27.5) | 43(35.8) | < 0.001 |
| Ciprofloxacin (Fluoroquinolones) | 71(59.2) | 10(8.3) | 39(32.5) | 59(49.2) | 17(14.2) | 44(36.7) | < 0.001 |
| Piperacillin (Β-Lactam) | 93(77.5) | 14(11.7) | 13(10.8) | 93(77.5) | 14(11.7) | 13(10.8) | 1 |
|
Piperacillin/Tazobactam (Beta-Lactamase Inhibitor) |
94(78.3) | 14(11.7) | 12(10) | 94(78.3) | 14(11.7) | 12(10) | 1 |
|
Ampicillin/Sulbactam (Beta-Lactamase Inhibitor) |
0(0) | 0(0) | 120(100) | 0(0) | 0(0) | 120(100) | - |
| Colistin (Polymyxin B) | - | 116(96.7) | 4(3.3) | - | 116(96.7) | 4(3.3) | - |
*Data were classified into sensitive and insensitive groups for statistical analysis. Intermediate group was considered as resistance