Statistical analysis results of the main metabolite change in feces at days 14 and 28^a.

Key	Metabolites	Chemical shift	Variations
			Day 14	Day 28
1	Caproate	0.887(t), 1.292(m), 1.309(m), 1.556(m), 2.178(t)	↑**	↑**
2	Valerate	0.899(t), 1.309(m), 2.178(d)	↑**	↑**
3	Butyrate	0.899(t), 1.562(m), 2.150(t)	↑**	↑**
4	Isoleucine	0.936(t), 0.995(d), 1.249(m), 1.452(m), 1.971(m), 3.655(d)	↓*	↓*
5	Valine	0.979(d), 1.013(d), 2.275(m), 3.617(d)	↓**	↓**
6	Propionate	1.061(t), 2.191(d)	↑*	↑*
7	α-Ketoisovalerate	1.127(d), 3.022(m)	↓*	↓*
8	Lactate	1.331(d), 4.115(q)	↓*	↑**
9	Cadaverine	1.483(d), 1.724(m), 3.022(t)	↓*	↓*
10	Alanine	1.489(d), 3.780(q)	↓*	↓*
11	Acetate	1.927(s)	↑**	↑**
12	Pyruvate	2.373(s)	↓*	↓*
13	Succinate	2.413(s)	↑**	↑**
14	Creatine	3.028(s), 3.926(s)	—	↓*
15	Taurine	3.243(t), 3.435(t)	—	↓*
16	Methanol	3.366(s)	↑**	↑**
17	Glycine	3.566(s)	↓**	↓**
18	Threonine	1.330(d), 3.579(d), 4.269(m)	↓*	↑**
19	Trimethylamine	2.871(s)	↓*	↓*
20	5-Aminovalerate	1.624(t), 1.650(t), 2.237(m), 3.022(m)	↓*	↓*
21	Methionine	2.141(s), 2.169(m), 2.648(t), 3.853(m)	↑**	↑**
22	Lysine	1.415(m), 1.719(m), 1.869(m), 3.018(t), 3.741(t)	↓*	↓*

^a*: indicates significant changes compared with control *p < 0.05, **p < 0.01.