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. Author manuscript; available in PMC: 2022 May 7.
Published in final edited form as: Pediatr Neurol. 2019 Dec 3;104:23–29. doi: 10.1016/j.pediatrneurol.2019.11.016

TABLE 3.

Remission Between Standard Therapies by Treatment Order

Treatment Model Odds Ratios* (95% CI), P value
ACTH versus VGB PRED versus VGB ACTH versus PRED
First Unadjusted 8.02 (2.94,21.88), P < 0.001 4.80(1.77, 12.98), P = 0.002 1.67 (0.60, 4.65), P = 0.33
Adjusted† 6.49 (2.27,18.55), P < 0.001 4.1 (1.45, 11.55), P = 0.008 1.58 (0.55, 4.59), P = 0.4
Second Unadjusted 1.80 (0.25,12.99), P = 0.56 1.71 (0.48, 6.16), P = 0.41 1.05 (0.14, 8.02), P = 0.96

Abbreviations:

ACTH = Adrenocorticotropic hormone

PRED = Prednisolone

VGB = Vigabatrin

For third treatment, there were not enough remissions for comparison.

*

Logistic regression used for the odds ratio estimates.

†

Adjusted for abnormal development, prior seizures, and etiology.