TABLE 5.
First Treatment | N | Remission After Treatment (%) | P |
---|---|---|---|
| |||
Initial remission | |||
Vigabatrin | 20 | 4 (20.0) | 0.006* |
ACTH | 20 | 14 (70.0) | |
Vigabatrin | 23 | 4 (17.4) | 0.004† |
Prednisolone | 23 | 14 (60.9) | |
Prednisolone | 19 | 9 (47.4) | 0.56† |
ACTH | 19 | 11 (57.9) | |
Three-month remission | |||
Vigabatrin | 20 | 9 (45.0) | 0.02* |
ACTH | 20 | 17 (85.0) | |
Vigabatrin | 23 | 7 (30.4) | 0.002† |
Prednisolone | 23 | 18 (78.3) | |
Prednisolone | 19 | 15 (79.0) | 0.99* |
ACTH | 19 | 14 (73.7) |
Matching variables: Age of spasm onset (≤6.25, >6.25, or unknown), spasm onset to first treatment (1 to 30 days, >30 days, or unknown), etiology, prior seizure, abnormal development.
Exact McNemar’s test
McNemar’s test