TABLE 2.
Baseline comorbidities
| Characteristic | No Onset (n = 85 076) | Onset (n = 4314) | P value |
|---|---|---|---|
| Hypertension | 50 336 (59.2) | 3024 (70.1) | <.0001 |
| Hyperlipidaemia | 50 636 (59.5) | 2993 (69.4) | <.0001 |
| Retinopathy | |||
| Other retinopathy | 795 (0.9) | 42 (1.0) | .7950 |
| Retinal oedema | 351 (0.4) | 15 (0.3) | .5150 |
| CSME | 430 (0.5) | 26 (0.6) | .3820 |
| Other retinal disorders | 294 (0.3) | 10 (0.2) | .2100 |
| Retinal detachment | 647 (0.8) | 37 (0.9) | .4750 |
| Blindness | 535 (0.6) | 32 (0.7) | .3620 |
| Neuropathy | |||
| Neurogenic bladder | 154 (0.2) | <10 | .7770 |
| Gastroparesis/diarrhoea | 174 (0.2) | 12 (0.3) | .3000 |
| Orthostatic hypotension | 1226 (1.4) | 57 (1.3) | .5190 |
| Cerebrovascular | |||
| TIA | 1486 (1.7) | 78 (1.8) | .7640 |
| Stroke | 5104 (6.0) | 288 (6.7) | .0690 |
| Cardiovascular | |||
| Atherosclerosis | 4216 (5.0) | 311 (7.2) | <.0001 |
| Other IHD | 675 (0.8) | 66 (1.5) | <.0001 |
| Angina pectoris | 1773 (2.1) | 155 (3.6) | <.0001 |
| Other chronic IHD | 10 445 (12.3) | 664 (15.4) | <.0001 |
| Myocardial infarction | 588 (0.7) | 37 (0.9) | .2000 |
| Ventricular fibrillation, arrest | 5508 (6.5) | 308 (7.1) | .0840 |
| Atrial fibrillation, arrest | 78 (0.1) | <10 | .3220 |
| Other ASCVD | 761 (0.9) | 55 (1.3) | .0100 |
| Old myocardial infarction | 2761 (3.2) | 197 (4.6) | <.0001 |
| Heart failure | 2673 (3.1) | 208 (4.8) | <.0001 |
| Atherosclerosis, severe | 38 (0.0) | <10 | .9590 |
| Aortic aneurysm/dissection | 1307 (1.5) | 52 (1.2) | .0830 |
| Peripheral vascular disease | |||
| Other aneurysm, LE | 35 (0.0) | <10 | .3770 |
| Foot wound + complication | 26 (0.0) | <10 | .7860 |
| Embolism/thrombosis (LE) | 75 (0.1) | <10 | .5520 |
| Ulcer of lower limbs | 493 (0.6) | 22 (0.5) | .5560 |
Note: Data are expressed as n (%). Baseline year = 2011.
Abbreviations: ASCVD, atherosclerotic cardiovascular disease; IHD, ischemic heart disease; LE, lower extremity; TIA, transient ischemic attack.