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Fig. 4. miR-155 downregulation partly abrogated SNHG5-knockdown-mediated anti-proliferation and pro-apoptosis effect in melanoma cells. A375 and SK-MEL-2 cells were transfected with si-con, si-SNHG5#2, and si-SNHG5#2 + anti-miR-155, followed by the measurement of miR-155 expression (A), cell viability (B), colony formation capability (C) and apoptosis rate (D). *P < 0.05.