TABLE 2.
In vitro susceptibilities of 522 incident isolates of C. neoformans to fluconazole
| MIC (μg/ml) | No. (%) of patients
|
||
|---|---|---|---|
| 1992 to 1994 | 1996 to 1998 | Total | |
| <8 | 89 | 142 | 231 (44) |
| 8 | 91 | 98 | 189 (37) |
| 16 | 62 | 23 | 85 (16) |
| 32 | 5 | 4 | 9 (1.6) |
| 64 | 3 | 2 | 5 (1) |
| 128 | 1 | 0 | 1 (0.1) |
| 256 | 2 | 0 | 2 (0.3) |
| Total | 253 | 269 | 522 |