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In vitro susceptibilities of 522 incident isolates of C. neoformans to itraconazole
| MIC (μg/ml) | No. (%) of patients
|
||
|---|---|---|---|
| 1992 to 1994 | 1996 to 1998 | Total | |
| 0.03 | 0 | 1 | 1 (0.2) |
| 0.06 | 1 | 14 | 15 (2.9) |
| 0.12 | 11 | 35 | 46 (8.8) |
| 0.25 | 89 | 111 | 200 (38.3) |
| 0.5 | 120 | 95 | 215 (41.2) |
| 1 | 31 | 12 | 43 (8.2) |
| 2 | 1 | 1 | 2 (0.4) |
| Total | 253 | 269 | 522 |
