TABLE 3.

In vitro susceptibilities of 522 incident isolates of C. neoformans to itraconazole

MIC (μg/ml)	No. (%) of patients
	1992 to 1994	1996 to 1998	Total
0.03	0	1	1 (0.2)
0.06	1	14	15 (2.9)
0.12	11	35	46 (8.8)
0.25	89	111	200 (38.3)
0.5	120	95	215 (41.2)
1	31	12	43 (8.2)
2	1	1	2 (0.4)
Total	253	269	522