Expression of integrin subunits on different functional-group-terminated surfaces.
| Functional groups | Integrin | Outcomes | References |
|---|---|---|---|
| Methyl group, CH3 | None | Maintain undifferentiated/quiescent state | 65 and 66 |
| Amine group, NH2 | α5, αv and β1 | Osteogenic differentiation | 65–67 |
| Carboxyl group, COOH | α5, β1, αv and β3 | Chrondogenic differentiation | 65 and 67 |
| Hydroxyl group, OH | α5, αv and β1 | Osteogenic and chrondogenic differentiation | 66, 68–70 |
| Phosphate group | αv and β1 | Osteogenic differentiation | 66 |