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. 2018 Feb 9;8(12):6551–6564. doi: 10.1039/c7ra12234a

Expression of integrin subunits on different functional-group-terminated surfaces.

Functional groups Integrin Outcomes References
Methyl group, CH3 None Maintain undifferentiated/quiescent state 65 and 66
Amine group, NH2 α5, αv and β1 Osteogenic differentiation 65–67
Carboxyl group, COOH α5, β1, αv and β3 Chrondogenic differentiation 65 and 67
Hydroxyl group, OH α5, αv and β1 Osteogenic and chrondogenic differentiation 66, 68–70
Phosphate group αv and β1 Osteogenic differentiation 66