Effect of MLAgNPs on the development of macroscopic hepatic nodules in different groups of ratsa.
| Treatment | Total no. of nodules | Tumour incidence (%) | Average number of nodules |
|---|---|---|---|
| Control | 0 | 0 | 0 |
| DEN | 107 | 100 | 54.86 ± 3.01z |
| DEN + sily | 14 | 21.38 | 4.16 ± 1.56c |
| DEN + MLE | 83 | 75.32 | 39.18 ± 2.10c |
| DEN + MLAgNPs20 | 32 | 34.03 | 9.65 ± 1.54c |
| DEN + MLAgNPs30 | 29 | 31.97 | 8.05 ± 1.26c |
a
Normal control group did not show any visual nodule on the liver. Data are presented as the mean ± SEM (n = 6) and analyzed as statistically significantly (xp < 0.05, yp < 0.01, zp < 0.001) compared to the normal control; (ap < 0.05, bp < 0.01, cp < 0.001) compared to the DEN control; ns, not significant.