Table 4.
Percentage of Patients Requiring AOT/NIV/MV/ECMO Support by Visit
| Parameter | Visit | Statistics | Favipiravir |
|---|---|---|---|
| N=1081 | |||
| n (%) | |||
| Overall oxygen therapy | Day 4 | n (%) | 7 (0.6) |
| 95% CI | (0.3, 1.3) | ||
| Day 7 | n (%) | 14 (1.3) | |
| 95% CI | (0.7, 2.2) | ||
| Day 10 | n (%) | 15 (1) | |
| 95% CI | (0.8, 2.3) | ||
| Day 14 | n (%) | 15 (1.4) | |
| 95% CI | (0.8, 2.3) | ||
| AOT | Day 4 | n (%) | 4 (0.4) |
| Day 7 | n (%) | 10 (0.9) | |
| Day 10 | n (%) | 11 (1.0) | |
| Day 14 | n (%) | 11 (1.0) | |
| NIV | Day 4 | n (%) | 3 (0.3) |
| Day 7 | n (%) | 5 (0.5) | |
| Day 10 | n (%) | 6 (0.6) | |
| Day 14 | n (%) | 6 (0.6) | |
| MV | Day 4 | n (%) | 0 |
| Day 7 | n (%) | 0 | |
| Day 10 | n (%) | 1 (0.1) | |
| Day 14 | n (%) | 1 (0.1) | |
| ECMO | Day 4 | n (%) | 0 |
| Day 7 | n (%) | 0 | |
| Day 10 | n (%) | 0 | |
| Day 14 | n (%) | 0 |
Notes: Percentages were based on the total number of patients in the mITT population. 95% Confidence interval was calculated using binomial proportion (exact method). Patients requiring more than oxygen support were counted only once under overall oxygen therapy.
Abbreviations: AOT, auxiliary oxygen therapy; ECMO, extracorporeal membrane oxygenation; mITT, modified intent-to-treat; MV, mechanical ventilation; N, number of patients in mITT; NIV, noninvasive ventilation.