Table 1.
Baseline Characteristics of the Study Population
| Characteristics | POCD Group (n=19) | Non-POCD Group (n=57) | P |
|---|---|---|---|
| Age (years) | 73.89±4.16 | 71.89±5.49 | 0.15 |
| Male(%) | 10(33.3%) | 20(66.7%) | 0.28 |
| ASA (I/II/III) | 4/12/3 | 14/40/3 | 0.39 |
| BMI(kg/m2) | 23.32±3.43 | 24.49±3.04 | 0.16 |
| Education (years) | 8.05±3.61 | 8.47±3.06 | 0.62 |
| MMSE scores | |||
| Preoperative | 26.63±1.92 | 27.26±1.62 | 0.17 |
| postoperative day 1 | 23.58±1.98 | 25.95±1.36 | <0.01 |
| postoperative day 3 | 25.84±1.64 | 26.84±1.65 | 0.03 |
| Operation duration (h) | 1.69±0.74 | 1.68±0.73 | 0.95 |
| Diabetes | 4 | 9 | 0.86 |
| Hypertension | 5 | 25 | 0.28 |
| Hyperlipemia | 0 | 5 | 0.32 |
| Heart disease | 1 | 5 | 0.62 |
| SII(109) | 934 (643–1065) | 388 (270–531) | <0.01 |
| NLR | 5.14 (3.41–7.49) | 2.12 (1.45–2.86) | <0.01 |
| MLR | 0.47 (0.39–0.66) | 0.27 (0.20–0.35) | <0.01 |
Abbreviations: ASA, American Society of Anesthesiologists; BMI, body mass index; MMSE, Mini-Mental State Examination; SII, systemic immune-inflammation index; NLR, neutrophil/lymphocyte ratio; MLR, monocyte/lymphocyte ratio; POCD, postoperative cognitive decline.