Table 3.

Summary of the TROP2 Relative Expression Levels, IC₅₀ and I_max Values of Diverse BC Cell Lines

Cell	Subtype	TROP2 Relative Expression	IC50 (nM)		Imax (%)
			MMAE	DS001	MMAE	DS001
MDA-MB-468	TNBC	57098	0.1102	0.3019	67.35	66.65
SK-BR-3	HER2+	48,206	0.0489	0.0245	75.64	74.83
MCF-10A	Fibroadenoma	41,671	0.3391	0.47	82.22	64.33
MCF7	Luminal A	30490	1.592	0.4261	61.63	27.25
HCC1806	TNBC	19182	0.0958	0.2512	74.46	71.31
MDA-MB-231	TNBC	5718	0.3787	145	61.99	59.68
MDA-MB-453	TNBC	1971	0.0715	117.5	65.75	55.64
SUM159	TNBC	7	0.5506	>300	75.42	−26.1

Abbreviations: BC, breast cancer; MMAE, monomethyl auristatin E; IC₅₀, half maximal inhibitory concentration; I_max, maximal inhibition rate.