Fig. 6. Anti-miR-29c-mediated suppression on type I IFN response was abated following STAT3 knockdown. RT-qPCR assay of PKR mRNA (A), OAS mRNA (B), IRF1 mRNA (C) expression and western bolt assay of PKR/OAS/IRF1 proteins expression (D) in Huh7 cells transfected with si-STAT3 or si-con. RT-qPCR assay of PKR mRNA (E), OAS mRNA (F), IRF1 mRNA (G) expression and western bolt assay of PKR/OAS/IRF1 proteins expression (H) in Huh7 cells transfected with anti-miR-29c alone, or together with si-STAT3. *P < 0.05 vs. corresponding control.
