TABLE 4.
Comparison of demographic and clinical factors for patients infected with ciprofloxacin-resistant versus fully susceptible E. coli isolates
| Characteristic | Ciprofloxacin susceptibility category
|
Odds ratio (95% CIa) | P | |
|---|---|---|---|---|
| Resistant (n = 9) | Fully susceptible (n = 57) | |||
| Median (range), age (yr) | 68 (11–88) | 52 (1–90) | 0.15 | |
| Male (no. [%] of patients) | 1 (11) | 12 (21) | 0.5 (0.02–4.5) | 0.7 |
| No. of days of prior hospitalization (mean [SD]) | 11.1 (16.3) | 5.1 (10.7) | 0.15 | |
| Underlying disease (no. [%] of patients) | ||||
| None | 0 | 17 (30) | 0 (0–1.6) | 0.01 |
| Renal | 1 (9) | 12 (21) | 0.5 (0.02–5.1) | 1.0 |
| Cancer | 8 (82) | 5 (9) | 83 (7.3–2,241) | <0.001 |
| Chronic liver disease | 2 (22) | 5 (9) | 3.0 (0.3–24) | 0.24 |
| Invasive device (no. [%] of patients) | ||||
| None | 0 | 6 (11) | 0.0 (0–6.6) | 0.59 |
| Peripheral intravenous line | 6 (67) | 38 (67) | 1.0 (0.2–5.8) | 1.0 |
| Urinary catheter | 2 (22) | 13 (23) | 0.97 (0.0–6.3) | 1.0 |
| Central venous catheter | 2 (22) | 7 (12) | 2.0 (0.23–14.9) | 0.6 |
| Receipt of any antibiotic over preceding 2 mo (no. [%] of patients) | 8 (89) | 16 (28) | 20.5 (2.2–482) | <0.001 |
| Receipt of quinolone antibiotic over preceding 2 mo (no. [%] of patients) | 2 (22) | 0 | Undefined | 0.02 |
| Receipt of nonquinolone antibiotic over preceding 2 mo (no. [%] of patients) | 8 (89) | 16 (28) | 20.5 (2.2–482) | <0.001 |
a
CI, confidence interval.