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. 2018 Mar 6;8(17):9487–9502. doi: 10.1039/c7ra13754k

Some of the starting materials and reagents used for the synthesis of arylnaphthalene lactone analogues.

Ref. Starting material(s) Reagent(s) Solvent Type 1 and type II ANL yields (%)
41 Arylpropargyl, arylpropiolate esters 4-Vinylpyridin, (P4-VP) Xylene 50–60
42 Phenylpropiolic acid, phenylpropargyl alcohol P4-VP, acid catalyst Xylene 45–50
43 Isovanillin Benzyl chloride Xylene 70–75
44 Diynes and arynes Pd catalyzed CH3CN 40–70
45 1-Phenyldihydronaphthofuran Jones reagent DMAc 20–30
46 Phenylpropargyl chloride, phenylacetylene Ag catalyzed DMA 16–30
47 AACMs Lewis acid CF3COOH 50–65