Some of the starting materials and reagents used for the synthesis of arylnaphthalene lactone analogues.
Ref. | Starting material(s) | Reagent(s) | Solvent | Type 1 and type II ANL yields (%) |
---|---|---|---|---|
41 | Arylpropargyl, arylpropiolate esters | 4-Vinylpyridin, (P4-VP) | Xylene | 50–60 |
42 | Phenylpropiolic acid, phenylpropargyl alcohol | P4-VP, acid catalyst | Xylene | 45–50 |
43 | Isovanillin | Benzyl chloride | Xylene | 70–75 |
44 | Diynes and arynes | Pd catalyzed | CH3CN | 40–70 |
45 | 1-Phenyldihydronaphthofuran | Jones reagent | DMAc | 20–30 |
46 | Phenylpropargyl chloride, phenylacetylene | Ag catalyzed | DMA | 16–30 |
47 | AACMs | Lewis acid | CF3COOH | 50–65 |