Table 4.
Connection between PD-L1 expression in cancerous cells and the cell count of CD4+T and CD8+T in peripheral blood, surrounding tissues, and cancer tissues.
| M (P25 and P75) | PD-L1 expression | Z | p | |
|---|---|---|---|---|
| Positive n (%) 35 (37.6) |
Negative n (%) 58 (62.4) |
|||
| Peripheral blood (cells/μl) | ||||
| CD4+T | 572.00 (483.00, 725.00) | 521.00 (359.76, 657.50) | 1.642 | 0.101 |
| CD8+T | 458.00 (341.00, 501.00) | 390.50 (249.25, 476.50) | 1.475 | 0.140 |
| CD4+T/CD8+T | 1.38 (1.15, 1.76) | 1.28 (1.09, 1.67) | 0.781 | 0.435 |
| Normal adjacent tissues (cells/HPF) | ||||
| CD4+T | 88.00 (49.40, 100.00) | 67.15 (48.40, 107.10) | 0.230 | 0.818 |
| CD8+T | 80.50 (50.30, 98.50) | 59.20 (36.78, 85.51) | 1.991 | 0.047 |
| CD4+T/CD8+T | 1.08 (0.67, 1.41) | 1.15 (0.82, 2.05) | 1.435 | 0.151 |
| Cancer tissues (cells/HPF) | ||||
| CD4+T | 70.00 (48.70, 115.60) | 49.99 (26.79, 77.42) | 2.657 | 0.008 |
| CD8+T | 90.70 (67.00, 127.50) | 56.50 (35.80, 85.42) | 3.799 | <0.001 |
| CD4+T/CD8+T | 0.70 (0.45, 1.26) | 0.90 (0.59, 1.27) | 1.277 | 0.202 |
Results are expressed as median (P25 and P75). Bold fonts are considered to have significant differences.