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. 2022 Apr 20;25(5):104269. doi: 10.1016/j.isci.2022.104269

Figure 6.

Figure 6

Location based clustering tendency of differentially expressed genes indicates global alteration of chromosome architecture in LOS

Shown are the genomic locations of differentially methylated regions (DMRs), differentially expressed genes (DEG) and predicted CTCF binding sites that overlap LOS DMRs. In addition, gene density and log10 transformed gene expression level per million bases are shown. The vertical location indicates level of misregulation for DMR and DEG, and sense (external) or antisense (internal) strands of CTCF binding sites. Mb = megabases. Note: track three (expression level) shows that for the most part the level of expression of genes globally is similar between LOS and controls.