Table 9.

Principle, sources, compounds extracted, and process conditions used in supercritical fluid extraction

Principle	Sources	Compounds extracted	Process conditions	References
Separating extract from the matrix using supercritical fluids like scCO2	Mentha spicata	Flavonoids (luteolin)	scCO2, pressure: 200 bar, 60 °C, and 60 min	Puri et al. 2012
	Feijoa leaf	Gallic acid, catechin, and isoquercetin	scCO2, 15% ethanol–water (as cosolvent), 210 min, pressure: 30 MPa, and 55 °C	Santos et al.. 2021
	Underutilized Chia seeds	Omega 3-rich oils (ALA and linoleic acid)	scCO2, pressure: 45 MPa, 60 °C, 240 min, and 40 g/min	Villanueva-Bermejo 2019
	Leaves of piper amalago	Pyrrolidine	scCO2, Co-solvents: ethanol, methanol, and propylene glycol 5% (v/v), pressure: 150, 200, and 250 bar, 40, 50, and 60 °C, 20, 40, and 60 min, CO2 flow rate: 3 mL/min, and particle size: 0.757 mm	Uwineza and Waskiewicz 2020
	Catharanthus roseus	Vinblastine and vincristine	scCO2, Co-S: ethanol 2, 5 and 10% (v/v), pressure: 300 bar T: 40, 50, and 60 °C
	Artemisia annua L	Artemisinin	scCO2, pressure: 100 bar, 40 °C, CO2 flow rate: 13.3–20 g/min
	Dried ivy leaves	Chlorophyll	scCO2, Co-S: ethanol (80/20 v/v), 25 °C, pressure: 15 MPa, and 30 min	Lefebvre et al. 2021
	Haematococcus pluvialis	Astaxanthin	scCO2, 50 °C, pressure: 50 MPa, 175 min, and flow rate: 2 L/min	Álvarez et al. 2020
	Rana chensinensis ovum	Rana chensinensis ovum oil (eicosapentaenoic acid, α-linolenic acid, docosahexaenoic acid, arachidonic acid, linoleic acid, and oleic acid)	scCO2, pressure: 29 MPa, flow: 82 L/h, 50 °C, and 132 min	Gan et al. 2020