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. 2018 Mar 27;8(21):11731–11743. doi: 10.1039/c8ra01125g

Analysis of variance of the experimental results of the BBD.

Variables Sum of squares DF Mean square F value P value
Model 27.51 9 3.06 69.92 <0.0001
X 1 0.012 1 0.012 0.27 0.6163
X 2 0.31 1 0.31 7.05 0.0327
X 3 1.07 1 1.07 24.55 0.0016
X 1 X 2 0.018 1 0.018 0.42 0.5391
X 1 X 3 0.27 1 0.27 6.19 0.0418
X 2 X 3 5.59 1 5.59 127.95 <0.0001
X 1 2 3.20 1 3.20 73.20 <0.0001
X 2 2 3.56 1 3.56 81.39 <0.0001
X 3 2 11.59 1 11.59 265.17 <0.0001
Residual 0.31 7 0.044
Lack of fit 0.081 3 0.027 0.48 0.7148
Pure error 0.23 4 0.056