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. 2022 May 2;19:429–443. doi: 10.1016/j.bioactmat.2022.04.017

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 7 — MAM/SRT accelerated the local bone healing of osteoporotic defect in rats. (A) Schematic for animal experiment. (B) X ray for bone healing after operation on weeks 3 and 5 in vivo. Red arrow represents defect area. (C) Microcomputed tomography (micro-CT) analysis of bone healing. (D–H) Bone mineral density (BMD), bone tissue volume/total tissue volume (BV/TV), trabecular number (Tb·N), trabecular thickness (Tb·Th), and trabecular separation (Tb.Sp) of ingrown bone tissue were assessed using micro-CT quantitatively analysis. (I–M) Bone mineral density (BMD), bone tissue volume/total tissue volume (BV/TV), trabecular number (Tb·N), trabecular thickness (Tb·Th), and trabecular separation (Tb.Sp) of the adjacent bone tissue were assessed using micro-CT quantitatively analysis. Data are expressed as the mean ± SD of three independent experiments, and one of three independent experiments is shown. *p < 0.05 vs. sham group. ^#p < 0.05 vs. AM group.