TABLE 1.

Distribution of pvdhfr mutations at five specific codons

Countries	Total no. of samples	No. of wild-type samples	No. of samples with mutation at codons for residue:
			33	57	58	117	173
Thailand	100	1	0	54a	99b	98	0
India	16	12	0	1c	3d	3	0
Madagascar and Comoros islands	9	5	4	0	0	0	0

^aIncluded 40 with mutant genotypes and 14 with mixed infections of wild-type and mutant genotypes. 

^bIncluded 98 with mutant genotypes and 1 with mixed infections of wild-type and mutant genotypes. 

^cBoth wild-type and mutant genotypes present. 

^dIncluded two with mutant genotypes and one with mixed infections of wild-type and mutant genotype.