Table 5.
Pearson’s correlation and statistical analyses of descriptors used in the QSAR model
| Inter-correlation | |||||||
|---|---|---|---|---|---|---|---|
| ATSC4e | AATSC4s | GATS2v | GATS8e | GATS6s | nsSeH | SssSnH2 | |
| ATSC4e | 1 | ||||||
| AATSC4s | 0.525345 | 1 | |||||
| GATS2v | 0.307996 | 0.028935 | 1 | ||||
| GATS8e | 0.478104 | 0.241975 | − 0.12161 | 1 | |||
| GATS6s | 0.62834 | 0.558828 | 0.260268 | 0.258477 | 1 | ||
| nsSeH | − 0.13871 | 0.184628 | − 0.43041 | − 0.03379 | 0.147126 | 1 | |
| SssSnH2 | 0.039192 | 0.270547 | − 0.04425 | 0.106862 | 0.24912 | 0.310204 | 1 |
| Statistical parameters | |||||||
|---|---|---|---|---|---|---|---|
| VIF | 2.630942 | 1.737761 | 1.631929 | 1.496797 | 2.174509 | 1.558148 | 1.229976 |
| ME | 0.138695 | 0.035656 | 0.518466 | 0.115025 | 0.15305 | − 0.05164 | 0.090747 |
| Coefficients | − 1.0679 | − 4.3793 | 4.035879 | 0.922556 | 1.10925 | − 0.09788 | 0.69691 |
| Std. Error | 0.181153 | 1.285964 | 1.23684 | 0.274962 | 0.268721 | 0.028934 | 0.127429 |
| t Stat | − 5.8953 | − 3.40544 | 3.263056 | 3.355218 | 4.127868 | − 3.38294 | 5.468995 |
| p-value | 2.40E−06 | 0.002014 | 0.002901 | 0.002292 | 0.000298 | 0.002134 | 7.71E−06 |