Table 3.
Demographic characteristics associated with loneliness in participants diagnosed as AD and pre-AD dementia status (SCD-MCI)1
| SCD-MCI | P | AD | P | |||
|---|---|---|---|---|---|---|
| Non-lonely (n = 20) | Lonely (n = 8) | Non-lonely (n = 17) | Lonely (n = 6) | |||
| Age | 75.3 ± 9.8 | 80.1 ± 7.6 | 0.180 | 77.8 ± 9.4 | 79.3 ± 10.7 | 0.495 |
| Sex (male, %) | 10 (50%) | 4 (50%) | 1.000 | 5 (29%) | 2 (25%) | 0.858 |
| Education (years) | 13.2 ± 1.96 | 11.3 ± 2.6 | 0.082 | 13.3 ± 2.9 | 11.7 ± 3.1 | 0.256 |
| ADAS-Jcog scores | ||||||
| Baseline | 10.1 ± 3.7 | 8.6 ± 3.4 | 0.322 | 16.7 ± 7.6 | 22.0 ± 9.6 | 0.184 |
| Annual change | − 0.2 ± 3.2 | 2.2 ± 2.5 | 0.080 | 2.8 ± 5.8 | 1.2 ± 3.0 | 0.390 |
1Values are expressed as mean ± SD. Calculated using two-tailed t-tests for continuous variables and the χ2 test for categorical variables. AD, patients with Alzheimer’s disease; ADAS-Jcog, Alzheimer’s Disease Assessment Scale-cognitive component-Japanese version; SCD-MCI, group containing patients with subjective cognitive decline and those with mild cognitive impairment