Fig. 1. Microencapsulated OMC in zeolitic imidazole frameworks for safe sunblock agent. (A) In situ micro-encapsulation diagram of OMC in ZIF-8 materials. Since the OMC molecular size is larger than the pore size of ZIF-8, the encapsulation could only be realized through the in situ process. (B) After sunlight exposure, free OMC produces deleterious ROS that could penetrate into skin tissue, and damages adjacent tissue. Microencapsulated OMC in ZIF-8 could confine these deleterious ROS species within the pore structure, and prevent ROS-mediated toxicity.