Fig. 1. Effect of 13 weeks of high fat fructose diet (HFFD) intake on IPGTT in rats. Values are expressed as mean ± S.E of 6 rats as compared to normal control group (*) (unpaired t-test), P < 0.05. Line graph showing the effect of high fat fructose diet + insulin (HFFD/insulin) on glucose tolerance test. The rats on HFFD/insulin exhibited an upward shift in the curve along the 2 h period, indicating a state of insulin resistance.